Test cost: 0 Rial

Status of test presentation: Existing

Sample type:

Tissue

 Formalin-fixed, paraffin-embedded tissue block

Sample size:

2 Unstained positively charged glass slide (25- x 75- x 1-mm) per test ordered; sections 4-microns thick.

 

Clinical information:

Mucin 1 (MUC1) was the first discovered trans‑ membrane protein of the mucin family; it normally covers epithelial cells of the mucous membrane, providing lubrica‑ tion and protection. However, aberrant expression of MUC1 is involved in cancer development, invasion and metastasis. It has been reported that MUC1 upregulation is highly associ‑ ated with the progression of different epithelial cancer types, such as lung, liver, pancreatic and breast cancer. Therefore, MUC1 can be used as a specific marker and a target for immu‑ notherapy in clinical applications, and the detection of MUC1 expression levels can be used to diagnose the occurrence, metastasis, prognosis and recurrence of cancer

Name of measurement method:

Immunohistochemistry (IHC)

Cases of non-acceptance of samples:

Wet/frozen tissue
Cytology smears
Nonformalin fixed tissue
Nonparaffin embedded tissue
Noncharged slides
ProbeOn slides