Test name: LH (IHC)
Test cost: 0 Rial
Status of test presentation: Existing
Sample type:
Teissu Formalin-fixed, paraffin-embedded (FFPE) tissue block
Sample size:
2 Unstained positively charged glass slide (25- x 75- x 1-mm) per test ordered; sections 4-microns thick
Clinical information:
In male individuals, luteinizing hormone (LH) stimulates androgen production by Leydig cells in the testis. In female individuals, LH stimulates androgen and progesterone synthesis in ovarian follicles and corpus luteum and promotes ovulation. A sparse population of cells (approximately 10%) stain positively in normal pituitary gland. This population of gonadotrophs also produces follicle-stimulating hormone. Immunohistochemical detection of LH beta may be useful in the classification of pituitary adenomas.
Intervening factors:
Age of a cut paraffin section can affect immunoreactivity. Stability thresholds vary widely among published literature and are antigen dependent. Best practice is for paraffin sections to be cut within 6 weeks.
Cases of non-acceptance of samples:
Wet/frozen tissue
Cytology smears
Nonformalin fixed tissue
Nonparaffin embedded tissue
Noncharged slides
ProbeOn slides