Test name: MIC2 (CD99) (IHC)
Test cost: 0 Rial
Status of test presentation: Existing
Sample type:
Tissue Formalin-fixed, paraffin-embedded tissue block
Sample size:
2 Unstained positively charged glass slide (25- x 75- x 1-mm) per test ordered; sections 4-microns thick.
Clinical information:
CD99 (cluster of differentiation 99) is the product of the MIC2 gene. It is expressed in normal tissues including some lymphocytes, pancreatic islet cells, granulosa cells of the ovary, Sertoli cells of the testis, and ependymal cells of the central nervous system. It is strongly expressed in Ewing sarcoma/primitive neuroectodermal tumor, distinguishing it from other small round blue cell tumors of childhood and adolescence.
Intervening factors:
Age of a cut paraffin section can affect immunoreactivity. Stability thresholds vary widely among published literature and are antigen dependent. Best practice is for paraffin sections to be cut within 6 weeks.
Cases of non-acceptance of samples:
Wet/frozen tissue
Cytology smears
Nonformalin fixed tissue
Nonparaffin embedded tissue
Noncharged slides
ProbeOn slides